1. Indication (86words) Edoxaban, a drug part of the direct factor Xa group is licensed on two indications. The first indication, treatment of pulmonary embolism (PE) and deep vein thrombosis (DVT). (1). Treatment is only conducted following the use of parenteral anticoagulants on a minimum 5-day course. Second, prevention of systemic embolism (SE) and stroke in nonvalvular atrial fibrillation (NVAF). Treatment conducted in line with […]
Introduction Cobalt was discovered by Georg Brandt in 1735 interestingly the name Cobalt originates form the German word “Kobald” which means goblin or evil spirit. The original use of cobalt was value to early civilisation of Egypt for colouring glass blue. Alfred Werner was a pioneer in coordination Chemistry determined the isomer cobalt (III) hexamine chloride. Experimental Ammonium chloride (1.306g) was dissolved in concentrate ammonia […]
Abstract The purpose of this experiment was to investigate the Ligand exchange that occurs when different Nickel complexes and reacted with Triphenylphosphine. Introduction Triphenylphosphine was first prepared by Pfeiffer and Sauvage in 1904 Experimental Triphenylphosphine (1.408g) was dissolved under reflux with Propan-2-ol (15cm3) forming a colourless solution to which 5 boiling chips were added. Nickel chloride hexahydrate (0.603g) was dissolved in absolute Ethanol (10cm3) and […]
The aim of this experiment is to investigate whether changing the concentration of a solution will have any effect on the rate of the reaction. We are trying to prove that increasing the concentration will speed up the rate of the reaction. The rate of a chemical reaction is the rate at which reactants are used up or products are produced. In order to measure […]
To determine the concentration of a Limewater Solution Aim To determine the concentration a 250 cm3 limewater solution, this contains approximately 1g dm-3 of calcium hydroxide. Also known is the concentration of HCL at 2.00mol dm-3. Introduction A titration method will be used to work out the concentration of the limewater But before the concentration of the limewater can be worked out, the correct concentration […]
Aim: To investigate how the rate of reaction between Sodium Thiosulphate and Hydrochloric acid is affected by changing the concentration. Background: THE REACTION: when Sodium Thiosulphate reacts with hydrochloric acid sulphur is produced. The sulphur forms in very small particles and causes the solution to cloud over and turn a yellow colour. This causes the cross to fade and eventually disappear. Sodium Thiosulphate + Hydrochloric […]
Question 1 Normal modes and vibrational frequencies of water molecule HF/3-21* optimised geometry of the water molecule H bond length 0.967 HOH bond angle 107.7˚ (ii) Energy of the HF/3-21G optimised water molecule = -75.58596 au Cycle Energy Max. Grad. Max. Dist. 1 75.58553 0.01246 0.00304 2 75.58589 0.00324 0.00025 3 75.58596 0.00001 0.00000 Frequency (cm-1) Relative Motion Stretch or Bend Type Symmetry (S or […]
INTRODUCTION “THE OZONE LAYER” The ozone layer is a portion of earth atmosphere that contains high levels of ozone. The atmosphere is divided into five layers: the troposphere, the stratosphere, the mesosphere, the thermosphere, and the exosphere. The troposphere is the layer closest to earth and is where all weather happenings occur. The stratosphere is located directly above the troposphere, about 10-50 kilometers above the […]
Results: Identify and mark the signals in the spectra and note the chemical shift values of the methyl resonances in aspirin and caffeine and the methylene resonance in s-trioxane. Using above expression, calculate the weight of aspirin and caffeine in one tablet, and the percentage w/w of each component in one analgesic tablet. Whole tablet weighed = 0.501 Half tablet weighed = 0.270 Mass of […]
Introduction What is a Calorimeter ? Definition: A calorimeter is a device used for calorimetry, the science of measuring the heat of chemical reactions or physical changes as well as heat capacity. The word calorimeter is derived from the Latin word calor, meaning heat. Differential scanning calorimeters, isothermal micro calorimeters, titration calorimeters and accelerated rate calorimeters are among the most common types. A simple calorimeter […]
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